Discusses the wiring of the central nervous system in human and the main properties of those circuitries. The course content covers broad range of circuitries including monosynaptic reflex and its modulation, inhibitory circuitries in the spinal cord as well as long and short term potentiation in hippocampal neurons, synaptic plasticity and transmission.
Aim of this course to discuss the basic neurophysiological and neuro-pathological processes in detail. The first part of the course will include basic neuro-pathophysiological mechanisms like calcium cytotoxicity, free radicals and free radical damage, protein aggregation disorders leading to neurodegeneration, apoptosis, and necrosis. Students have assignment for making a presentation regarding one of the pathophysiological mechanism. At the second part of the course pathophysiological processes leading to neuro psychiatric disorders like epilepsy, headache and pain, psychosis, anxiety disorders, subarachnoid hemorrhage and trauma will be discussed in detail. Before fina examination, student have to present a journal paper regarding disease mechanisms learned.
Aim of this course is to introduce the basic subjects of neurobiology, including cellular and morphological details, molecular biology and electrophysiology as well as functional anatomy of the central and the peripheral nervous system. Neurotransmitters, neuromediators and interneuronal interactions will be discussed. There will be introduction lectures on the mechanisms of neurological and psychiatric diseases.
The main purpose of this course is to provide a better understanding of sleep medicine and sleep disorders. The course will address the neurophysiological, cardiovascular, respiratory and endocrine mechanisms involved in sleep regulation as well as genetics of sleep and chronobiology. Instrumentation and methods such as polysomnography recordings and scoring of sleep stages will be presented. Students will be introduced to the multidisciplinary field of sleep medicine and be able to describe the main categories of sleep disorders including insomnia, narcolepsy, parasomnias and sleep-related breathing disorders. Initially, each participant will choose a scientific research paper relevant to the course content to review during the course period. These papers will be presented in the last session of the course and the paper work will be evaluated as part of the final grading.
This course covers the pharmacology of the nervous system with special emphasis on mechanisms of action of different drugs acting on the synaptic transmission. At the center will be the seminal question: “How brain works, and how structure-behavior relationship is established? The course intends to introduce the basics of the synaptic transmission and drug sensitive sites in synaptic transmission. The components of the integrative chemical communications in the central nervous system will be taken all along the course with the clinical use of different therapeutic drug groups. Priority will be given to explore experimental models in a historical context.
The use of animal models provides significant information in the understanding of the physiology and pathophysiology of nervous system diseases and disorders in humans. The purpose of this course is to understand the depth of knowledge regarding the methodological principles and concepts in animal models. This course will give students an introduction to basic physiological, anatomical and histological characteristics of laboratory animals. On completion of this course, the students will be familiar with the animal models best suited to study human nervous system disease and disorders.
This course is non-credit and aims to increase the scientific interaction between students and improve their presentation skills with the participation of students from all interdisciplinary programs. The Seminar course which is consisting of presentation of the studies and researches in front of the community within the framework of the techniques determined with the guidance of the advisor, and question and answer part are graded each semester.
This course is non-credit course which the supervisor evaluates the student's thesis work. It covers all the studies and researches to be carried out on the thesis subject determined by the guidance of the advisor and is graded each semester by the advisor.